Adolescence is a period of human brain growth and high incidence of mental health disorders. In 2016 the Neuroscience in Psychiatry Network published a study of adolescent brain development which showed that the hubs of the structural connectome are late developing and are found in association cortex (http://dx.doi.org/10.1073/pnas.1601745113). Furthermore these regions are enriched for genes related to schizophrenia. In this presentation Dr Kirstie Whitaker will demonstrate how this work is supported by open data and analysis code, and that the results replicate in two independent cohorts of teenagers. She will encourage Brainhack-Global participants to take steps towards ensuring that their work meets these standards for open and reproducible science in 2017 and beyond.